The Pill

Combined pill (COC)

Effectiveness:
Over 99 per cent effective if taken according to instructions. Less than one woman in 100 will get pregnant in a year.

How it works:
Contains two hormones – estrogen and progestogen. It stops ovulation, thickens cervical mucus to prevent sperm reaching an egg and thins the lining of the uterus to prevent a fertilised egg implanting.

Advantages:
• Often reduces bleeding, period pain and pre-menstrual symptoms.
• Protects against cancer of the ovary, uterus and colon and some pelvic infections.
• Suitable for healthy non-smokers up to the menopause.
• When you stop using the combined pill your fertility will return to normal.

Disadvantages:
• Not suitable for very overweight women or smokers over 35 years old.
• Very low risk but serious side-effects may include blood clots (thrombosis), breast cancer and cervical cancer.
• Can be temporary side-effects such as headaches, nausea, mood changes and breast tenderness.

Comments:
• Missing pills, vomiting or severe, long-lasting diarrhoea can make it less effective.
• Some medicines can make it less effective.
• Breakthrough bleeding and spotting is common in the first few months.


Progestogen-only pill (POP)

Effectiveness:
Over 99 per cent effective if taken according to instructions. Less than one woman in 100 will get pregnant in a year.

How it works:
Contains the hormone progestogen, which thickens cervical mucus to prevent sperm reaching an egg and thins the lining of the uterus to prevent a fertilised egg implanting. In some women it stops ovulation.

Advantages:
• No serious side-effects.
• Can be used by women who cannot use estrogen.
• Can be used by women who smoke and are over 35.
• You can use it if you are breastfeeding.

Disadvantages:
• Periods may stop, or be irregular, light, or more frequent.
• May be temporary side-effects such as acne, weight change and headaches.
• A small increased risk of ectopic pregnancy if it fails.
• May be less effective in women who weigh over 70kg (11 stone).
• May get ovarian cysts.

Comments:
• It needs to be taken at the same time each day.
• Not effective if taken over three hours late (12 hours for Cerazette) or after vomiting or severe, long-lasting diarrhoea.
• Some medicines may make it less effective but most common antibiotics do not affect POPs.
NHS Choices